~~*FiBrOaDeNoMa*~~

Fibroadenoma of the breast is a benign fibroepithelial tumor characterized by proliferation of both glandular and stromal elements.

The typical case is the presence of a painless, firm, solitary, mobile, slowly growing lump in the breast of a woman of childbearing years.

In the male breast, fibroepithelial tumors are very rare, and are mostly Phyllodes tumors. Exceptionally rare case reports exist of fibroadenomas in the male breast, however these cases may be associated with antiandrogen treatment.

A fibroadenoma is usually diagnosed through clinical examination, ultrasound or mammography, and often a needle biopsy sample of the lump.

>>>aku ariya doc pake needle biopsy...huhuhu sakit aih. gila pa...ntah pa dikorek2 di cucuk2 dikikis and disedut2 pake jarum ya...eeeeWW

Fibroadenomas arise in the terminal duct lobular unit of the breast. They are the most common breast tumor in adolescent women. They also occur in a small number of post-menopausal women. Their incidence declines with increasing age, and they generally appear before the age of thirty years, probably partly as a result of normal estrogenic hormonal fluctuation. Although fibroadenoma is considered a neoplasm, some authors believe fibroadenoma arises from hyperplasia of normal breast lobule components.

Most fibroadenomas are treated by surgical excision. They are removed with a small margin of normal breast tissue if the preoperative clinical investigations are suggestive of the diagnosis. A small amount of normal tissue must be removed in case the lesion turns out to be a phyllodes tumour on microscopic examination.

Because needle biopsy is often a reliable diagnostic investigation, some doctors may decide not to operate to remove the lesion, and instead opt for clinical follow-up to serially observe the lesion over time using clinical examination and mammography to determine the rate of growth, if any, of the lesion. A growth rate of less than sixteen percent per month in women under fifty years of age, and a growth rate of less than thirteen percent per month in women over fifty years of age have been published as safe growth rates for continued non-operative treatment and clinical observation. Fibroadenomas have not been shown to recur following complete excision or transform into phyllodes tumours following partial or incomplete excision.

Fibroadenoma, Fine Needle Aspiration Biopsy (Papanicolou stain). The image shows a sheet of epithelial cells in the typical antler pattern.